2018 41:2265‐2274.Here’s a breakdown of how to use the monitor. Clinical implications of real‐time and intermittently scanned continuous glucose monitoring. 2017 8:55‐73.Įdelman SV, Argento NB, Pettus J, Hirsch IB. Flash glucose‐sensing technology as a replacement for blood glucose monitoring for the management of insulin‐treated type 2 diabetes: a multicenter, open‐label randomized controlled trial. Haak T, Hanaire H, Ajjan R, Hermanns N, Riveline J‐P, Rayman G. Flash glucose monitoring improves outcomes in a type 1 diabetes clinic. Novel glucose‐sensing technology and hypoglycaemia in type 1 diabetes: a multicentre, non‐masked, randomised controlled trial. 2018 24:309‐311.īolinder J, Antuna R, Geelhoed‐Duijvestijn P, Kröger J, Weitgasser R. An endocrine clinic's perspective and experience with the Abbott Freestyle Libre Cgm. The remaining authors have no relevant conflicts of interest to disclose.īlum JR, Rayfield EJ. has received honoraria as well as travel and educational grant support from Boehringer‐Ingelheim, Eli Lilly and Company, Novo Nordisk and Sanofi‐Aventis. has received research grants, including those for principal investigator, collaborator or consultant and pending grants, as well as other grants, from Health Care and Research Wales (Welsh Government) and Novo Nordisk has received research support from Healthcare and Research Wales (Welsh Government), honoraria from Novo Nordisk, Sanofi, Lilly, Boehringer Ingelheim and Merck, and has an ownership interest in Glycosmedia, an on‐line news service concerning diabetes. has received honoraria, travel support or unrestricted research grants from Amgen, Astra Zeneca, Boehringer‐Ingelheim, Eli Lilly, MSD, Novo Nordisk and Sanofi‐Aventis. has received a KESS2/European Social Fund scholarship and travel grants from Novo Nordisk A/S. has received lecture fees from Medtronic, travel grants from Novo Nordisk A/S, Novo Nordisk AT, Novo Nordisk UK, Medtronic AT, research grants from Sêr Cymru II COFUND fellowship/European Union, Novo Nordisk A/S and Novo Nordisk AT, as well as material funding from Abbott Diabetes Care. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd. The overall MARD during acute exercise was 29.8% (17.5%-39.8%), during hypoglycaemia was 45.1% (35.2%-51.1%), during euglycaemia was 30.7% (18.7%-39.2%) and during hyperglycaemia was 16.3% (10.0%-22.8%).įlash GM interstitial glucose readings were not sufficiently accurate within the hypoglycaemic range and during acute exercise and require confirmatory blood glucose measurements.Ĭontinuous glucose monitoring (CGM), exercise intervention, hypoglycaemia, type 1 diabetes. Overall Bland-Altman analysis showed a bias (95% LoA) of 1.26 mmol/L (-1.67 to 4.19 mmol/L). Flash GM accuracy was assessed by median absolute relative difference (MARD) (interquartile range ) using the Bland-Altman method and Clark error grid, as well as according to guidelines for integrated CGM approvals (Class II-510(K)). Venous blood glucose and capillary blood glucose during exercise was compared to interstitial glucose concentrations. Throughout the four 14-hour inpatient phases, 19 participants received three carbohydrate-rich meals and performed moderate-intensity exercise. This study comprised four randomized trial visits with alternating pre- and post-exercise bolus insulin doses. This study aimed to determine the performance of the flash GM system during daily-life glycaemic challenges such as carbohydrate-rich meals, bolus insulin-induced glycaemic disturbances and acute physical exercise in individuals with type 1 diabetes. The efficacy of flash glucose monitoring (flash GM) systems has been demonstrated by improvements in glycaemia however, during high rates of glucose flux, the performance of continuous glucose monitoring systems was impaired, as detailed in previous studies.
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